Welcome to Şen Lab
Receptorology Proteomics Structures

Unraveling the mysteries of physical and chemical regulatory
mechanisms in protein function



Our research interests lie in the structural and functional basis of receptor–ligand interactions, which are relevant to human health and disease. Much of our studies aim to elucidate the molecular recognition properties governing receptor interactions with a ligand, and subsequent molecular events that couple ligand recognition to receptor activation. Many of the systems we study are related to the interactions between the host cell and environmental cues.

Structural studies are then complemented by functional approaches using molecular biology and protein engineering to dissect structural information, design proteins or peptides with modified specificities and activities, and ultimately contribute to the development of biologics with therapeutic potential.

The αXβ2 integrin

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Who We Are

Meet the diverse group of people who make our research environment unique.


What We Know

Students of Dr. Şen can click on the portal to be redirected to his Teaching page.


Where We Are

The Şen Lab is a constituent member of the University of Houston.

What We Do

The Şen Lab is a multidisciplinary group that encompasses people from
various talents and backgrounds.

Molecular Biology

The study of life through the lenses of macromolecules.


Metabolic and chemical processes within living organisms.


Physical phenomena in life, and the mathematics that explain them.